UltraPlex mxIF Plus for Immuno-Oncology

UltraPlex mxIF (multiplex immunofluorescence) is a paradigm-shifting technology that addresses the needs of precision medicine

With UltraPlex mxIF Plus you can phenotype your tumor sample and identify infiltrating lymphocytes with two tissue sections in two hours. Want to additionally look at PD-L1 expression on APCs and tumor? Add another serial section, it still takes just two hours!

Cell IDx developed UltraPlex, a proprietary, modified hapten-based technology to address the need for unrestricted, simple, rapid, and simultaneous detection of multiple cellular markers in tissue sections. Our individual panels consist of four markers plus DAPI as a nuclear marker to enumerate total cell number. With UltraPlex Plus, tissue alignment of two or three sequential sections labeled with individual four-plex UltraPlex mxIF panels provides an unsurpassed capacity for cellular analysis, generating a comprehensive map of cellular composition, localization, and marker expression in situ.

The combination of Cell IDx’s cancer phenotyping panels with immune marker panels on serial sections can generate rapid, accurate information on tumor phenotype, infiltrating immune subpopulations, levels of marker expression per cell, and individual cellular localization in situ relative to other immune cells or tumor.

Immune Infiltration of Triple-Negative Breast Cancer

CK5 (green), EGFR (red), Vimentin (blue), Ki-67 (magenta)

Overlay of 2 serial sections

CD3 (cyan), CD4 (thallium), CD8 (orange), CD20 (blue)

  • “A” multiplex panels are linked to 490, 550, 650, and 750nm fluors.
  • “B” multiplex panels are linked to 490, 550, 590, and 650nm fluors. Available soon, please contact us for more information.
  • Single stain controls for generating a spectral library for use with “B” multiplex panels are available separately. Available soon, please contact us for more information.
  • Please select the appropriate panel for use with your imaging scanner or microscope.

Order from our range of available panels or contact us to create a Custom RUO Panel for you.

Click on Catalog # to view detailed product information.

Product Name Description Size Catalog # List Price Quantity Add to Cart
BC-1A mxIF Panel - HER2, ER, PR, Ki-67 490, 550, 650, 750 nm fluors 1 slide BC01A-001 $400
BC-1A mxIF Panel - HER2, ER, PR, Ki-67 490, 550, 650, 750 nm fluors 10 slides BC01A-010 $3,750
BC-1A mxIF Panel - HER2, ER, PR, Ki-67 490, 550, 650, 750 nm fluors 100 slides BC01A-100 $0
BC-2A mxIF Panel - CK5, EGFR, Vimentin, Ki-67 490, 550, 650, 750 nm fluors 1 slide BC02A-001 $400
BC-2A mxIF Panel - CK5, EGFR, Vimentin, Ki-67 490, 550, 650, 750 nm fluors 10 slides BC02A-010 $3,750
BC-2A mxIF Panel - CK5, EGFR, Vimentin, Ki-67 490, 550, 650, 750 nm fluors 100 slides BC02A-100 $0
HI-1A mxIF Panel - CD3, CD4, CD8, CD20 490, 550, 650, 750 nm fluors 1 slide HI01A-001 $400
HI-1A mxIF Panel - CD3, CD4, CD8, CD20 490, 550, 650, 750 nm fluors 10 slides HI01A-010 $3,750
HI-1A mxIF Panel - CD3, CD4, CD8, CD20 490, 550, 650, 750 nm fluors 100 slides HI01A-100 $0
HI-2A mxIF Panel - CD68, CD163, Pan-CK, PD-L1 490, 550, 650, 750 nm fluors 1 slide HI02A-001 $400
HI-2A mxIF Panel - CD68, CD163, Pan-CK, PD-L1 490, 550, 650, 750 nm fluors 10 slides HI02A-010 $3,750
HI-2A mxIF Panel - CD68, CD163, Pan-CK, PD-L1 490, 550, 650, 750 nm fluors 100 slides HI02A-100 $0
HI-4A mxIF Panel - CD8, CD68, Pan-CK, PD-L1 490, 550, 650, 750 nm fluors 1 slide HI04A-001 $400
HI-4A mxIF Panel - CD8, CD68, Pan-CK, PD-L1 490, 550, 650, 750 nm fluors 10 slides HI04A-010 $3,750
HI-4A mxIF Panel - CD8, CD68, Pan-CK, PD-L1 490, 550, 650, 750 nm fluors 100 slides HI04A-100 $0
HI-5A mxIF Panel - CD8, CD68, PD-1, PD-L1 490, 550, 650, 750 nm fluors 1 slide HI05A-001 $400
HI-5A mxIF Panel - CD8, CD68, PD-1, PD-L1 490, 550, 650, 750 nm fluors 10 slides HI05A-010 $3,750
HI-5A mxIF Panel - CD8, CD68, PD-1, PD-L1 490, 550, 650, 750 nm fluors 100 slides HI05A-100 $0
HN-1A mxIF Panel - EGFR, CK5, Vimentin, Ki-67 490, 550, 650, 750 nm fluors 1 slide HN01A-001 $400
HN-1A mxIF Panel - EGFR, CK5, Vimentin, Ki-67 490, 550, 650, 750 nm fluors 10 slides HN01A-010 $3,750
HN-1A mxIF Panel - EGFR, CK5, Vimentin, Ki-67 490, 550, 650, 750 nm fluors 100 slides HN01A-100 $0

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