UltraPlex^™ Technology

Fluorescent & Chromogenic Multiplex IHC Staining Technology

UltraPlex fluorescent multiplex immunohistochemistry and chromogenic multiplex immunohistochemistry comprise a paradigm-shifting technology that addresses the needs of precision medicine for multiplex IHC detection of proteins on tissues.

Cell IDx has developed a proprietary, Tag-based technology to address the need for unrestricted, simple, rapid, and simultaneous detection of multiple biomarkers in any immunoassay. The underpinnings of the technology comprise novel Tag design and their detection with high affinity anti-Tag antibodies. Initially, we have directed our UltraPlex technology to the development of fluorescent multiplex IHC and chromogenic multiplex IHC tissue-based assays. Methods for chromogenic and fluorescent detection of multiple markers have long been an unmet need. Our UltraPlex technology presents solutions to both assays overcoming many limitations.

UltraPlex Features

1° antibody species-independent
Standard two-step immunoassay protocols
Single antigen retrieval step for tissue staining
Signal intensities equivalent to anti-species antibody detection

High-throughput compatible
Potential for unlimited multiplexing
Tag labeling can be incorporated into any immunoassay & detection technology
Compatible with existing instrumentation